A rapid and sensitive 86Rb efflux assay to detect chemical compounds capable of modulating the ATP-dependent potassium (KATP) channel is described. This assay, which is performed in a 96-well microtiter plate, utilizes Ugg Gloves Stockists Uk
a substrate adherent cell line as the target, requires a small amount of 86Rb as the tracer, and is a suitable system for performing the biochemical and pharmacological characterization of the KATP-channel and its activators. Because this assay is amenable to automation, it presents a useful means for high-volume screening of chemical compounds on a routine basis.
On a recent geophysical pipeline route survey between the SW coast of Norway and the Cheap Ugg Boots
Ekofisk oil field in the North Sea a submerged beach deposit was discovered. The beach is located on the shoulder of the SW slope of the Norwegian Trench at a water depth of 90 m.The beach is similar in structure to a submerged beach previously described for a deposit located 380 km further NNW in the same type of regional environment (the shoulder of the Western Slope). This beach is, however, located 40–70 m deeper, suggesting a possible post-glacial dipping of the North Sea Plateau.